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ASSESSMENT OF ANTICOAGULANT EFFECT OF EVENING PRIMROSE OIL
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نویسنده
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RIAZ AZRA ,KHAN RAFEEQ ALAM ,AHMED SHAHIDA PARVEEN
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منبع
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pakistan journal of pharmaceutical sciences - 2009 - دوره : 22 - شماره : 4 - صفحه:355 -359
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چکیده
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Effect of evening primrose oil (epo) was assessed on coagulation parameters following 30 and 60 days administration of 90, 180 and 360 μl/kg oil to healthy rabbits of either sex. there was significant increase in all assays except fibrinogen time. these effects might be due to inactivation or inhibition of factors affecting coagulation. the intake of evening primrose oil also significantly decreased platelet count. results of this study suggest that evening primrose oil shows considerable anti-anticoagulant and anti-platelet activity in animals and has potential to reduce cardiovascular morbidity and mortality.
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کلیدواژه
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Evening primrose oil ,Thrombin time ,Prothrombin time ,activated partial thromboplastin time ,Fibrinogen time
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آدرس
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University of Karachi, Department of Pharmacology, Pakistan, University of Karachi, Department of Pharmacology, Pakistan, University of Karachi, Department of Pharmacology, Pakistan
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Authors
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