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3-[(2-chloroquinolin-3-yl)methyl]quinazolin-4(3H)-ones as potential larvicidal agents
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نویسنده
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Roopan Selvaraj Mohana ,Khan Fazlur-Rahman Nawaz ,Jin Jong Sung
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منبع
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pakistan journal of pharmaceutical sciences - 2013 - دوره : 26 - شماره : 4 - صفحه:747 -750
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چکیده
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The larvicidal effect of series of 3-[(2-chloroquinolin-3-yl)methyl]quinazolin-4(3h)-ones, 5a-e, against chironomus tentans fabricius has been investigated. the results showed that tested compounds demonstrated strong larvicidal activity, and caused high percentage of mortality after 24 h at the doses of 40-100 μg/ml, especially in the case of 3-[(2-chloro-8-methyquinolin-3-yl)methyl]quinazolin-4(3h)-one, 5b, that act as a promising larvicidal agent.
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کلیدواژه
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Larvicidal activity ,3-[(2-chloroquinolin-3-yl)methyl]quinoline-4(3H)-ones ,synthesis
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آدرس
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VIT University, School of Advanced Sciences, Organic & Medicinal Chemistry Research Laboratory, Organic Chemistry Division, India, VIT University, School of Advanced Sciences, Organic & Medicinal Chemistry Research Laboratory, Organic Chemistry Division, India. Korea Basic Science Institute, Busan center, South Korea, Korea Basic Science Institute, Busan center, South Korea
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Authors
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