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ANTIDIARRHOEAL AND ANTIULCER ACTIVITIES OF HIPPOCRATEA AFRICANA ROOT EXTRACT
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نویسنده
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OKOKON JUDE EFIOM ,AKPAN HENRY DAN ,UMOH EMEM EKPO ,EKAIDEM ITEMOBONG SUNDAY
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منبع
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pakistan journal of pharmaceutical sciences - 2011 - دوره : 24 - شماره : 2 - صفحه:201 -205
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چکیده
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The effect of ethanol root extract of h. africana on experimentally induced diarrhoea and ulcer was studied in rodents. the extract (200 – 600mg/kg) considerably inhibited castor oil induced diarrhoea, small intestine transit time and castor oil induced fluid accumulation as well as indomethacin and ethanol induced ulcer models. the effect of the extract in these models was comparable to the various standard drugs used. the root extract of h. africana has antidiarrhoeal and antiulcer properties which justify its uses in ethnomedicine.
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کلیدواژه
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Hippocratea africana ,antidiarrhoea ,antiulcer ,rodents.
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آدرس
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University of Uyo, Faculty of Pharmacy, Department of Pharmacology and Toxicology, Nigeria, University of Uyo, Faculty of Basic Medical Sciences, College of Health Sciences, Department of Biochemistry, Nigeria, University of Uyo, Faculty of Pharmacy, Department of Pharmacology and Toxicology, Nigeria, University of Uyo Teaching Hospital, Department of Chemical Pathology, Nigeria
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Authors
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