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ANTIOXIDANT ACTIVITY OF COVOLVULUS HYSTRIX VAHL AND ITS CHEMICAL CONSTITUENTS
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نویسنده
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DONIA ABD EL RAHEIM MOHAMMED ,ALQASOUMI SALEH IBRAHIM ,AWAAD AMANI SHAFEEK ,CRACKER LYLE
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منبع
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pakistan journal of pharmaceutical sciences - 2011 - دوره : 24 - شماره : 2 - صفحه:143 -147
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چکیده
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Total alcohol and successive extracts (diethyl ether, chloroform, ethyl acetate and n-butanol) of covolvulus hystrix vahl were screened for their antioxidant activity using free radical 2-2- diphenyl-1-picrylhydrazyl (dpph) and trolox as reference substance. the tested extracts showed variable antioxidant activities. the highest antioxidant activity was achieved in total alcohol (48.32%) followed by ethyl acetate (37. 8 %) and nbutanol (32.96 %) extracts. from the ethyl acetate extract four compounds were isolated and identified as quercetin, quercetin 3-0-rutinoside and quercetin-7-o-rhamnoside in addition to ferulic acid using different spectroscopic analysis such as, 1hnmr, 13cnmr, cosy, hmbc and hmqc.
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کلیدواژه
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Antioxidant activity ,Convolvulus hystrix ,flavonoids ,ferulic acid ,total phenolics.
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آدرس
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Desert Research Center, Medicinal and Aromatic Plants Department, Egypt. Al Kharj University, College of Pharmacy, Pharmacognosy Department, Saudi Arabia, Al Kharj University, College of Pharmacy, Pharmacognosy Department, Saudi Arabia, King Saud University, College of Science, Chemistry Department, Saudi Arabia, University of Massachusetts, Department of Plant Soil & Insect Sciences, Saudi Arabia
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Authors
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