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HEPATOPROTECTIVE ACTIVITY OF PHYLLANTHUS RETICULATUS
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نویسنده
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DAS BIPLAB K. ,BEPARY SUKUMAR ,DATTA BIDYUT K. ,CHOWDHURY A. K. AZAD ,ALI MOHAMMAD SHAWKAT ,ROUF ABU SHARA SHAMSUR
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منبع
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pakistan journal of pharmaceutical sciences - 2008 - دوره : 21 - شماره : 4 - صفحه:333 -337
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چکیده
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Two partially purified organic fractions designated by pr1 and pr2 of the fat free ethanol (95%) extract of aerial parts of phyllanthus reticulatus were tested for the hepatoprotective activity in rats against ccl4-induced liver damage. the rats receiving the fractions showed promising hepatoprotective activity as evident from significant changes of pentobarbital-induced sleeping time, changes in serum levels of sgpt, sgot, salp and bilirubin and also from histopathological changes as compared to ccl4-intoxicated rats.
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کلیدواژه
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Phyllanthus reticulatus ,organic fractions ,hepatoprotective activity ,CCl4-induced liver damage
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آدرس
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East West University, Department of Pharmacy, Bangladesh, East West University, Department of Pharmacy, Bangladesh, University of Dhaka, Department of Pharmaceutical Technology, Bangladesh, University of Dhaka, Department of Clinical Pharmacy and Pharmacology, Bangladesh, University of Dhaka, Department of Clinical Pharmacy and Pharmacology, Bangladesh, University of Dhaka, Department of Pharmaceutical Technology, Bangladesh
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Authors
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