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SIMULTANEOUS ESTIMATION OF ATORVASTATIN AND RAMIPRIL BY RP-HPLC AND SPECTROSCOPY
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نویسنده
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JOSEPH LINCY ,GEORGE MATHEW ,RAO B VENKATA RANGA
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منبع
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pakistan journal of pharmaceutical sciences - 2008 - دوره : 21 - شماره : 3 - صفحه:282 -284
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چکیده
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A number of analytical methods were reported for the estimation of atorvastatin and ramipril from their individual dosage forms or in combination with other drugs (valiyare, 2004; vachareau and neirinck, 2000). here successful reverse phase-high performance liquid chromatographic method and spectroscopic methods developed then validated for the analysis of combined dosage form of atorvastatin and ramipril . individual λ- max for atorvastatin is 247 n.m and that of ramipril is 208 n.m. they intercept at 215 n.m which is fixed as wavelength for reverse phase-high performance liquid chromatographic method.
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کلیدواژه
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Atorvastatin ,Ramipril ,RP-HPLC ,intersil-ODS ,Acetonitrile ,Vierodt’s equation
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آدرس
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Mekelle University, School of Pharmacy, Ethiopia, Mekelle University, School of Pharmacy, Ethiopia, Mekelle University, School of Pharmacy, Ethiopia
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Authors
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