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Anti-stress and anti-allergic effect of Actiniopteris radiata in some aspects of asthma
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نویسنده
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Vadnere Gautam Prakash ,Pathan Aslam Ramjan ,Singhai Abhay Kumar ,Kulkarni Bharti Uday ,Hundiwale Jogendra Chandrakant
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منبع
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pakistan journal of pharmaceutical sciences - 2013 - دوره : 26 - شماره : 1 - صفحه:195 -198
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چکیده
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Successive extracts of whole plant of actiniopteris radiata screened for its therapeutic potential as an antiallergic and antistress agent in asthma using specific in vivo animal models. only ethanol extract (aree) at a higher dose of 100 mg/kg i.p significantly (p<0.05) decreased milk induced eosinophilia by 16.20 ± 2.235 when compared with control group while even lower doses of 50 mg/kg, i.p exhibited significant inhibition (p<0.05) of leukocytosis induced by milk in mice. other extracts like petroleum ether, ethyl acetate and methanol unable to exhibit that significant potential. results obtained thus validate the traditional claim of the actiniopteris radiata utilization in different aspect of asthma due to presence of various polar secondary metabolites in ethanol extract.
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کلیدواژه
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Actiniopteris radiata; leucocytosis ,eosinophilia ,anti-stress ,anti-allergic ,asthma
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آدرس
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Smt. SS Patil College of Pharmacy, India, Smt. SS Patil College of Pharmacy, India, Department of Pharmaceutical Sciences, India, Smt. SS Patil College of Pharmacy, India, Smt. SS Patil College of Pharmacy, India
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Authors
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