Analgesic,anti-inflammatory and anti-pyretic activities of Thymus Linearis

The present study was aimed to investigate the antipyretic,analgesic and anti-inflammatory activity of aqueous methanolic and n-hexane extract of thymus linearis. for measuring analgesic activity,writhing test,hot plate method and formalin test were performed and abdominal writhing was induced by intra-peritoneal injection of 0.2 ml of 3% acetic acid. while in formalin test,pain was experimentally induced by injecting 25 μl of 2.5% formalin in left hind paw. in hot plate method,pain was induced thermally by keeping the animals on a hot plate with temperature of about 51°c. anti-inflammatory activity was assessed by carrageenan induced mice paw edema. for determination of antipyretic activity,pyrexia was induced by subcutaneous injection of 15% yeast. the results showed that both the extracts had significant analgesic activity (p<0.05); anti-inflammatory activity (p<0.05) and anti-pyretic activity (p<0.05). therefore,it was concluded from this study that the extracts of thymus linearis may be used against pain,pyrexia and inflammation.