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Antiviral potential of a diterpenoid compound sugiol from Metasequoia glyptostroboides
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نویسنده
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bajpai v.k. ,kim n.-h. ,kim k. ,kang s.c.
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منبع
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pakistan journal of pharmaceutical sciences - 2016 - دوره : 29 - شماره : 3 - صفحه:1077 -1080
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چکیده
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This research reports first time antiviral activity of sugiol,a diterpenoid isolated from metasequoia glyptostroboides in terms of its ability to inhibit in vitro growth of h1n1 influenza virus. antiviral potential of sugiol was evaluated through hcytopathogenic reduction assay using madin-darby canine kidney (mdck) cell line. sugiol (500 μg/ml) was found to exhibit considerable anti-cytopathic effect on mdck cell line confirming its antiviral efficacy against h1n1 influenza virus. these findings strongly reinforce the suggestion that sugiol could be a candidate of choice in combinational regimen with potential antiviral efficacy.
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آدرس
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department of applied microbiology and biotechnology,school of biotechnology,yeungnam university,gyeongsan, Korea, department of oriental pharmacy,wonkwang university,iksan-city,jeonbuk, Korea, division of biotechnology,college of environmental and bioresource sciences,chonbuk national university,gobong-ro,iksan-si,joellabuk-do (jeonbuk), Korea, department of biotechnology,college of engineering,daegu university,gyeongsan,gyeongbuk, Korea
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Authors
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