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Impact of bovine and human serum albumin on Curcumin in vitro activity against Staphylococcus aureus
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نویسنده
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teow s.y. ,ali s.a.
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منبع
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pakistan journal of pharmaceutical sciences - 2017 - دوره : 30 - شماره : 3 - صفحه:891 -895
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چکیده
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This study evaluated the impact of ph (7.4 and 6.5),bovine serum albumin (bsa),and human serum albumin (hsa) on curcumin activity against 2 reference,1 clinical,and 10 environmental strains of staphylococcus aureus (s. aureus). minimal inhibitory concentrations (mics) of curcumin against s. aureus were statistically indifferent (p>0.05) at ph7.4 and ph6.5. activity of curcumin against s. aureus was reduced by two folds in the presence of 1.25-5% bsa/hsa.
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کلیدواژه
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Antibacterial activity; Curcumin; Plasma protein binding; Serum albumin; Staphylococcus aureus
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آدرس
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cluster of oncological and radiological sciences,advanced medical and dental institute (amdi),university sains malaysia (usm),bertam,kepala batas,pulau pinang, Malaysia, cluster of oncological and radiological sciences,advanced medical and dental institute (amdi),university sains malaysia (usm),bertam,kepala batas,pulau pinang, Malaysia
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Authors
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