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Screening of the Anti-hyperglycemic activity of some medicinal plants of Jordan
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نویسنده
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alkofahi a.s. ,abdul-razzak k.k. ,alzoubi k.h. ,khabour o.f.
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منبع
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pakistan journal of pharmaceutical sciences - 2017 - دوره : 30 - شماره : 3 - صفحه:907 -912
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چکیده
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Diabetes represents a group of common diseases that are characterized by dysregulation of blood glucose levels. plants are traditionally used for management of diseases including diabetes. in this study,we screened the antidiabetic effect of extracts of 21 plants grown in jordan. extracts of plants were screened for their antihyperglycemic activity. diabetes was induced in sprague dawley rats using alloxan. plant extracts were dosed at 1gm/kg. blood glucose was measured at baseline and at every hour for 3 hours. results showed that five plants out of the 21 screened showed antihyperglycemic activity. these plants are phoenix dactylifera l.,tecoma stans (l.) kunth,cichorium pumilum jacq.,phaseolus vulgaris l.,and teucrium polium l. on the other hand,sarcopoterium spinosum (l.) spach. and brassica oleracea l. var. capitata significantly increased blood glucose levels in diabetic rats. the following plant extracts showed neutral effect on blood glucose levels: plantago major l.,taraxacum cyprium h. lindb,artemisia inculta delile,marrubium vulgare l.,inula viscosa (l.) ai,rubus sanguineus friv,coriandrum sativum l.,cucurbita pepo var ovefera,cucumis sativus l.,hordeum vulgare l.,apium graveolens l.,avena sativa l.,helianthus annus l.,and anethum graveolens l. in conclusion,jordanian medicinal plants might be useful for managements of blood glucose levels in patients with diabetes.
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کلیدواژه
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Antihyperglycemic; Diabetes; Plant extract
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آدرس
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department of medicinal chemistry and pharmacognosy,faculty of pharmacy,jordan university of science and technology,irbid, Jordan, department of clinical pharmacy,faculty of pharmacy,jordan university of science and technology,irbid, Jordan, department of clinical pharmacy,faculty of pharmacy,jordan university of science and technology,irbid, Jordan, department of medical laboratory sciences,faculty of applied medical sciences,jordan university of science and technology,irbid, Jordan
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Authors
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