COMBINED STRATEGIES TO CONTROL ANTINEMATICIDAL -RESISTANT GASTROINTESTINAL NEMATODES IN SMALL RUMINANTS ON ORGANIZED FARMS IN PAKISTAN

Antinematicidal resistance has been rooted on all the continents particularly in areas where ovine and caprine are being reared intensively due to frequent annual use of broad-spectrum dewormers. farmers rely on mono-strategic scheme by using synthetic drugs to treat their livestock which is deemed the easier way to control gastrointestinal nematode infections as compared to the other strategies. on the other hand, recurrent employment of antinematicidal chemotherapeutics has conduced to development and prevalence of resistance among nematode populations. in this regard, other advocating strategies such as grazing management, rotation of antinematicidal drugs (although it is too late), amelioration of animal immunity, genetic approaches, biological control, nutritional supplementation, avoidance of mass treatment, improvement of management, eradication of concurrent diseases, and phytotherapy should be considered too. although, by far there are no commercialized substantial alternatives to chemotherapy, but the current substitutes could decrease the parasitic burden, which, in turn, restrict indiscriminate use of synthetic drugs. the resistance is more rampant on organized farms as compared to non organized farms in rural areas in asian, african and south latin american countries because tamed animal raisers in those areas depend on ethnobotanicals to treat parasitism due to high cost of allopathic drugs. therefore, in this review, the different strategies to control the antinematicidal resistance on organized farms in pakistan will be elaborated.