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BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
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نویسنده
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Dudnik Alexey ,Almeida A. Filipa ,Andrade Ricardo ,Avila Barbara ,Bañados Pilar ,Barbay Diane ,Bassard Jean-Etienne ,Benkoulouche Mounir ,Bott Michael ,Braga Adelaide ,Breitel Dario ,Brennan Rex ,Bulteau Laurent ,Chanforan Celine ,Costa Inês ,Costa Rafael S. ,Doostmohammadi Mahdi ,Faria Nuno ,Feng Chengyong ,Fernandes Armando ,Ferreira Patricia ,Ferro Roberto ,Foito Alexandre ,Freitag Sabine ,Garcia Gonçalo ,Gaspar Paula ,Godinho-Pereira Joana ,Hamberger Björn ,Hartmann András ,Heider Harald ,Jardim Carolina ,Julien-Laferriere Alice ,Kallscheuer Nicolai ,Kerbe Wolfgang ,Kuipers Oscar P. ,Li Shanshan ,Love Nicola ,Marchetti-Spaccamela Alberto ,Marienhagen Jan ,Martin Cathie ,Mary Arnaud ,Mazurek Vincent ,Meinhart Camillo ,Sevillano David Méndez ,Menezes Regina ,Naesby Michael ,Nørholm Morten H. H. ,Okkels Finn T. ,Oliveira Joana ,Ottens Marcel ,Parrot Delphine ,Pei Lei ,Rocha Isabel ,Rosado-Ramos Rita ,Rousseau Caroline ,Sagot Marie-France ,Santos Claudia Nunes dos ,Schmidt Markus ,Shelenga Tatiana ,Shepherd Louise ,Silva Ana Rita ,Silva Marcelo Henriques da ,Simon Olivier ,Stahlhut Steen Gustav ,Solopova Ana ,Sorokin Artem ,Stewart Derek ,Stougie Leen ,Su Shang ,Thole Vera ,Tikhonova Olga ,Trick Martin ,Vain Philippe ,Veríssimo André ,Vila-Santa Ana ,Vinga Susana ,Vogt Michael ,Wang Liangsheng ,Wang Lijin ,Wei Wei ,Youssef Sandra ,Neves Ana Rute ,Forster Jochen
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منبع
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phytochemistry reviews - 2018 - دوره : 17 - شماره : 2 - صفحه:291 -326
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چکیده
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Bacterial hosts for production of bioactive phenolics from berry fruits (bachberry) was a 3-year project funded by the seventh framework programme (fp7) of the european union that ran between 2013 and 2016. the overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. the project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of gram-positive bacterial cell factories producing phenolic compounds. further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. this review article summarizes some of the key findings obtained throughout the duration of the project.
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کلیدواژه
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Berries ,Bioprospecting ,Microbial cell factories ,Polyphenols ,Sustainable production
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آدرس
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Technical University of Denmark, Denmark, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Institut National de Recherche en Informatique et Automatique, France, Pontificia Universidad Católica de Chile, Chile, Pontificia Universidad Católica de Chile, Chile, Evolva, Switzerland, University of Copenhagen, Department of Plant and Environmental Science, Denmark, Evolva, Switzerland, Institut für Bio- und Geowissenschaften, Germany, Biotempo, Portugal. University of Minho, Portugal, John Innes Centre, UK, James Hutton Institute, UK, Institut National de Recherche en Informatique et Automatique, France, Chr. Hansen Natural Colors A/S, Denmark, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Universidade de Lisboa, Portugal, Universidade de Lisboa, Portugal. University of Edinburgh, UK, Biotempo, Portugal. University of Minho, Portugal, The Chinese Academy of Sciences, China, Universidade de Lisboa, Portugal, Biotempo, Portugal. University of Minho, Portugal, Technical University of Denmark, Denmark, James Hutton Institute, UK, James Hutton Institute, UK, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Technical University of Denmark, Denmark, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, University of Copenhagen, Department of Plant and Environmental Science, Denmark, Universidade de Lisboa, Portugal, Evolva, Switzerland, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Institut National de Recherche en Informatique et Automatique, France, Institut für Bio- und Geowissenschaften, Germany, Biofaction KG, Austria, University of Groningen, Department of Molecular Genetics, The Netherlands, The Chinese Academy of Sciences, China, John Innes Centre, UK, Institut National de Recherche en Informatique et Automatique, France, Institut für Bio- und Geowissenschaften, Germany, John Innes Centre, UK, Institut National de Recherche en Informatique et Automatique, France, Chr. Hansen Natural Colors A/S, Denmark, Biofaction KG, Austria, Delft University of Technology, Department of Biotechnology, The Netherlands, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Evolva, Switzerland, Technical University of Denmark, Denmark, Chr. Hansen Natural Colors A/S, Denmark, Biotempo, Portugal. University of Minho, Portugal, Delft University of Technology, Department of Biotechnology, The Netherlands, Institut National de Recherche en Informatique et Automatique, France, Biofaction KG, Austria, Biotempo, Portugal. University of Minho, Portugal, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Evolva, Switzerland, Institut National de Recherche en Informatique et Automatique, France, Instituto de Biologia Experimental e Tecnológica, Portugal. Universidade Nova de Lisboa, Portugal, Biofaction KG, Austria, N. I. Vavilov Research Institute of Plant Industry, Fruit Crops Genetic Resources Department, Russia, James Hutton Institute, UK, Biotempo, Portugal. University of Minho, Portugal, Delft University of Technology, Department of Biotechnology, The Netherlands, Chr. Hansen Natural Colors A/S, Denmark, Technical University of Denmark, Denmark, University of Groningen, Department of Molecular Genetics, The Netherlands, N. I. Vavilov Research Institute of Plant Industry, Fruit Crops Genetic Resources Department, Russia, James Hutton Institute, UK. Heriot Watt University, UK, University of Edinburgh, UK. Centrum Wiskunde & Informatica, Netherlands, The Chinese Academy of Sciences, China, John Innes Centre, UK, N. I. Vavilov Research Institute of Plant Industry, Fruit Crops Genetic Resources Department, Russia, John Innes Centre, UK, John Innes Centre, UK, Universidade de Lisboa, Portugal, Universidade de Lisboa, Portugal, Universidade de Lisboa, Portugal, Institut für Bio- und Geowissenschaften, Germany, The Chinese Academy of Sciences, China, The Chinese Academy of Sciences, China, The Chinese Academy of Sciences, China, Biofaction KG, Austria, Chr. Hansen Holding A/S, Denmark, Technical University of Denmark, Denmark
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