Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry

Procyanidins are polyphenols abundant in dietary fruits, vegetables, nuts, legumes, and grains with a variety of chemopreventive biological effects. rapid structure determination of these compounds is needed, notably for the more complex polymeric procyanidins. we review the recent developments in the structure elucidation of procyanidins with a focus on mass spectrometric approaches, especially liquid chromatography-tandem mass spectrometry (lc–ms/ms) and matrix-assisted laser desorption ionization (maldi) ms/ms.