DELAYED RENAL GRAFT FUNCTION IN THE EARLY POST-TRANSPLANT PERIOD AND ITS IMPACT ON THE LATE POST-TRANSPLANT RESULTS

Delayed renal graft function (dgf) is a frequent complication with negative impact on the courseof early post-transplantation period. the data concerning the impact on the late results are contradictory.this study describes results of 5-year follow-up of 248 recipients after deceased donorrenal transplantation. all patients were divided into two groups: with delayed graft function (dgf,n = 53) and immediate graft function, considered as the control group (igf, n = 195). we evaluatedfactors that were associated with development of dgf and its impact on the survival of graftand recipient, and frequency of acute rejections and chronic dysfunctions. the rate of observeddgf was 21.4%. its development was associated with the following factors: age of recipient andtheir weight, age of donor and their body mass index, high frequency of asystole/hypotension indonors prior to organ explantation (p < 0.05 for all), and longer time of cold ischemia (p = 0.058).the dgf group had higher rate of acute rejections (p < 0.001), and also lower 1.5 and 5-yeargraft survival and 1.5-year patient survival (p < 0.05 for all). the conclusion is that dgf hasnegative impact on the survival of renal grafts and patients, especially during the first 1.5 yearsafter transplantation.