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Evaluation of radioactivity in the bodies of mice induced by neutron exposure from an epi-thermal neutron source of an accelerator-based boron neutron capture therapy system
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نویسنده
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nakamura s. ,imamichi s. ,masumoto k. ,ito m. ,wakita a. ,okamoto h. ,nishioka s. ,iijima k. ,kobayashi k. ,abe y. ,igaki h. ,kurita k. ,nishio t. ,masutani m. ,itami j.
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منبع
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proceedings of the japan academy series b-physical and biological sciences - 2017 - دوره : 93 - شماره : 10 - صفحه:821 -831
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چکیده
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This study aimed to evaluate the residual radioactivity in mice induced by neutron irradiation with an accelerator-based boron neutron capture therapy (bnct) system using a solid li target. the radionuclides and their activities were evaluated using a high-purity germanium (hp-ge) detector. the saturated radioactivity of the irradiated mouse was estimated to assess the radiation protection needs for using the accelerator-based bnct system. 24na,38cl,80mbr,82br,56mn,and 42k were identified,and their saturated radioactivities were (1.4 ± 0.1) # 102,(2.2 ± 0.1) # 101,(3.4 ± 0.4) # 102,2.8 ± 0.1,8.0 ± 0.1,and (3.8 ± 0.1) # 101 bq/g/ma,respectively. the 24na activation rate at a given neutron fluence was found to be consistent with the value reported from nuclear-reactor-based bnct experiments. the induced activity of each nuclide can be estimated by entering the saturated activity of each nuclide,sample mass,irradiation time,and proton current into the derived activation equation in our accelerator-based bnct system. © 2017 the japan academy.
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کلیدواژه
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Accelerator-based BNCT; Boron neutron capture therapy (BNCT); Induced radioactivity; Radioactivation
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آدرس
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department of radiation oncology,national cancer center hospital,tokyo,japan,department of physics,rikkyo university,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo,japan,division of genetics,national cancer center research institute,tokyo, Japan, high energy accelerator research organization (kek),ibaraki, Japan, division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo,japan,department of radiological technology,national cancer center hospital,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo,japan,department of radiological technology,national cancer center hospital,tokyo, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan, department of physics,rikkyo university,tokyo, Japan, department of medical physics,graduate school of medicine,tokyo women's university,tokyo, Japan, division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo,japan,division of genetics,national cancer center research institute,tokyo,japan,department of frontier life sciences,nagasaki university graduate school of biomedical sciences,nagasaki, Japan, department of radiation oncology,national cancer center hospital,tokyo,japan,division of research and development for boron neutron capture therapy,national cancer center exploratory oncology research and clinical trial center,tokyo, Japan
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Authors
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