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Xanthones from calophyllum inophyllum
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نویسنده
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lee k.w. ,ee g.c.l. ,daud s. ,karunakaran t.
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منبع
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pertanika journal of tropical agricultural science - 2017 - دوره : 40 - شماره : 1 - صفحه:111 -118
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چکیده
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Repeated separation and purifcation of fractions from the crude chloroform extract of calophyllum inophyllum via column chromatography afforded fve known xanthone caloxanthones a,b,c,macluraxanthone and pyranojacareubin. structural elucidations and determination of the isolated compounds were supported by spectral analyses obtained by subjecting the compounds to various spectroscopic techniques. the chloroform extract,when tested against raw264.7 cells for anti-inflammatory potentials,exhibited the most promising activity with an ic50 value of 14.81±0.04 μg/ml compared to moderate activities shown by the ethyl acetate and n-hexane extracts. antimicrobial tests showed that the n-hexane and chloroform extracts acted moderately against staphylococcus epidermidis s273 and bacillus subtilis b145. © universiti putra malaysia press.
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کلیدواژه
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Anti-inflammatory; Antimicrobial; Calophyllum inophyllum; Xanthones
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آدرس
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department of chemistry,faculty of science,universiti putra malaysia,serdang,selangor, Malaysia, department of chemistry,faculty of science,universiti putra malaysia,serdang,selangor, Malaysia, department of chemistry,faculty of science,universiti putra malaysia,serdang,selangor,malaysia,department of chemistry,faculty of applied science,universiti teknologi mara,uitm,jengka,pahang, Malaysia, department of chemistry,faculty of science,universiti putra malaysia,serdang,selangor, Malaysia
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Authors
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