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suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of persian medicine
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نویسنده
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ده پرور نجمه ,علیجانیها فاطمه ,مظفرپور سید علی ,نیاسری نسلجی امیر ,بهاءالدین زهرا ,گرشاسبی احیاء ,غلامی فشارکی محمد ,ناصری محسن
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منبع
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journal of medicinal plants - 2022 - دوره : 21 - شماره : 83 - صفحه:1 -10
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چکیده
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Background: according to the reverse pharmacological method, traditional medicine has a good source of information for discovering new drug candidates. polycystic ovarian syndrome (pcos) is the most common cause of endocrine disorder and infertility among women of reproductive age. this syndrome is commonly treated by oral contraceptive pills; however, it could be associated with side effects. objective: the purpose of this study was to identify and prioritize medicinal plants proposed by persian medicine (pm) for the treatment of pcos. methods: the first step was to find out the most relevant keywords to the symptoms of pcos among five authentic pm manuscripts because there was no medical term called pcos in pm texts. according to those keywords, all materia medicas that was described in the selected books were recorded. each materia medica received scores based on specific criteria. the scores were used to prioritize medicaments. results: ferula assa-foetida l., tanacetum parthenium l., lycium barbarum, cymbopogon schoenanthus l., lepidium sativum l. and marrubium vulgare were six top materia medica identified in this study. conclusion: identification of closely related terminology for pcos in traditional medical texts and prioritization of herbal remedies could be a sound approach to discover new drugs. accordingly, ferula assa-foetida l. with the highest score was considered the best candidate for the treatment of pcos in pm.
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کلیدواژه
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drug discovery ,persian medicine ,polycystic ovarian syndrome ,reverse pharmacology ,traditional medicine
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آدرس
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shahed university, faculty of medicine, department of traditional persian medicine, iran, , iran. shahed university, faculty of medicine, traditional medicine clinical trial research center, department of traditional persian medicine, iran, babol university of medical sciences, traditional medicine and history of medical sciences research center, health research institute, iran, university of tehran, faculty of veterinary medicine, department of theriogenology, iran, , iran. shahed university, faculty of medicine, traditional medicine clinical trial research center, department of traditional persian medicine, iran, shahed university, medical school, obstetrics and gynecology department, iran, tarbiat modares univesity, faculty of medicine, department of biostatistics, iran, , iran. shahed university, faculty of medicine, traditional medicine clinical trial research center, department of traditional persian medicine, iran
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پست الکترونیکی
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naseri@shahed.ac.ir
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suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of persian medicine
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Authors
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dehparvar najmeh ,alijaniha fatemeh ,mozaffarpur ali ,niasari-naslaji amir ,bahaedin zahra ,garshasbi ahia ,gholami-fesharak mohammad ,naseri mohsen
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Abstract
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background: according to the reverse pharmacological method, traditional medicine has a good source of information for discovering new drug candidates. polycystic ovarian syndrome (pcos) is the most common cause of endocrine disorder and infertility among women of reproductive age. this syndrome is commonly treated by oral contraceptive pills; however, it could be associated with side effects. objective: the purpose of this study was to identify and prioritize medicinal plants proposed by persian medicine (pm) for the treatment of pcos. methods: the first step was to find out the most relevant keywords to the symptoms of pcos among five authentic pm manuscripts because there was no medical term called pcos in pm texts. according to those keywords, all materia medicas that was described in the selected books were recorded. each materia medica received scores based on specific criteria. the scores were used to prioritize medicaments. results: ferula assa-foetida l., tanacetum parthenium l., lycium barbarum, cymbopogon schoenanthus l., lepidium sativum l. and marrubium vulgare were six top materia medica identified in this study. conclusion: identification of closely related terminology for pcos in traditional medical texts and prioritization of herbal remedies could be a sound approach to discover new drugs. accordingly, ferula assa-foetida l. with the highest score was considered the best candidate for the treatment of pcos in pm.
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Keywords
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drug discovery ,persian medicine ,polycystic ovarian syndrome ,reverse pharmacology ,traditional medicine
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