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effects of imfluna, an iranian traditional polyherbal medicine, on covid-19 symptoms: a randomized, double-blind and placebo-controlled clinical trial
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نویسنده
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fallah huseini hasan ,gholibeikian mohammadreza ,shohrati majid ,kaffash afsaneh ,taheri ali ,khajepour hojatolah ,raei mehdi ,kianbakht saeed ,fallah hosseini amena ,ghorbani nohooji majid ,mohtashami reza
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منبع
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journal of medicinal plants - 2022 - دوره : 21 - شماره : 81 - صفحه:51 -66
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چکیده
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Background: the current pandemic of coronavirus disease 2019 (covid19) and severity of the infection and high mortality have almost unprecedented challenges in the health systems of most countries around the world. objective: the present study aimed to evaluate the effect of iranian traditional polyherbal medicine (imfluna) containing a mixture of echinacea, stachys, artemisia, hyssopus, polybody, alpinia, ginger, and ginseng extract on symptoms of covid19 infected patients. methods: in this placebocontrolled and doubleblind clinical trial, a total of 60 voluntarily approved patients with covid19 were randomly assigned to the placebo and imfluna groups. patients in each group, in addition to receiving standard medications, took two 500 mg capsules of imflona or placebo every 8 hours for 2 weeks. the patient #39;s vital signs, including the severity of shortness of breath, cough, and body temperature, were recorded during the study. also blood esr, liver and kidney function tests were performed at baseline and endpoint. results: the results showed that patients in the imflunatreated group had significantly greater improvement in daily cough, shortness of breath and esr compared with the placebo group. in addition, lung lesions improved in the imflunatreated group, although not significantly. conclusion: patients with covid19 who were treated with imfluna for 2 weeks had better comfort and fewer symptoms associated with the disease with no any drug side effects.
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کلیدواژه
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clinical trial ,covid-19 ,polyherbal medicine ,iranian traditional ,medicine ,imfluna
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آدرس
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acecr, medicinal plants research center, institute of medicinal plants, iran, university of kashan, faculty of chemistry, department of organic chemistry, iran, baqiyatallah uiversity of medical sciences, faculty of pharmacy, department of pharmacotherapy, iran, sabzevar university of medical sciences, faculty of medicine, department of internal medicine, iran, baqiyatallah university of medical sciences, faculty of pharmacy, iran, baqiyatallah university of medical sciences, department of radiology, iran, baqiyatallah university of medical sciences, health research center, life style institute, iran, acecr, medicinal plants research center, institute of medicinal plants, iran, tehran university of medical sciences, department of emergency medicine, iran, acecr, medicinal plants research center, institute of medicinal plants, iran, baqiyatallah university of medical sciences, medicine quran and hadith research center, iran
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پست الکترونیکی
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reza_mohtashami1979@bmsu.ac.ir
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Effects of Imfluna, an Iranian traditional polyherbal medicine, on COVID-19 symptoms: A randomized, double-blind and placebo-controlled clinical trial
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Authors
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Fallah Huseini Hasan ,Gholibeikian Mohammadreza ,Shohrati Majid ,Kaffash Afsaneh ,Taheri Ali ,Khajepour Hojatolah ,Raei Mehdi ,Kianbakht Saeed ,Fallah Hosseini Amena ,Ghorbani Nohooji Majid ,Mohtashami Reza
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Abstract
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Background: The current pandemic of Coronavirus disease 2019 (COVID19) and severity of the infection and high mortality have almost unprecedented challenges in the health systems of most countries around the world. Objective: The present study aimed to evaluate the effect of Iranian traditional polyherbal medicine (Imfluna) containing a mixture of echinacea, stachys, artemisia, hyssopus, polybody, alpinia, ginger, and ginseng extract on symptoms of COVID19 infected patients. Methods: In this placebocontrolled and doubleblind clinical trial, a total of 60 voluntarily approved patients with COVID19 were randomly assigned to the placebo and Imfluna groups. Patients in each group, in addition to receiving standard medications, took two 500 mg capsules of Imflona or placebo every 8 hours for 2 weeks. The patient #39;s vital signs, including the severity of shortness of breath, cough, and body temperature, were recorded during the study. Also blood ESR, liver and kidney function tests were performed at baseline and endpoint. Results: The results showed that patients in the Imflunatreated group had significantly greater improvement in daily cough, shortness of breath and ESR compared with the placebo group. In addition, lung lesions improved in the Imflunatreated group, although not significantly. Conclusion: Patients with COVID19 who were treated with Imfluna for 2 weeks had better comfort and fewer symptoms associated with the disease with no any drug side effects.
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Keywords
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Clinical trial ,COVID-19 ,Polyherbal medicine ,Iranian traditional ,medicine ,Imfluna
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