Study on Chemical Composition of Essential oil and Anti-oxidant and Anti Microbial Properties of Artemisia haussknechtii

Background: artemisia species with common persian name of dermaneh are found all overiran and are used for treatment in infectious diseases such as malaria, hepatitis and otherdiseases. some artemisia species are used in traditionally as tonic and anti-helmintic in north ofiran.objective: the aim of this study was to investigate chemical composition of the essential oil ofartemisia haussknechtii. also potential antioxidant and anti microbial activities of the essential oiland ethanolic extract were studied.methods: the essential oil was prepared by hydrodistillation and analyzed by gc and gc/msinstruments. antioxidant activity was evaluated by methods; namely dpph, free radicalscavenging, ftc system and total phenolic compounds analyzing. the antimicrobial activities ofthe extract were individually tested against a panel of microorganisms using disc diffusionmethod and mic (minimum inhibitory concentration) measurement.results: forty-eight components were identified constituting 98.35 of total oil. camphor(12.4%), α-terpineol (9.93%), davana ether (6/24%), and bornyl acetate (3.77%) were the majorcomponents. good antioxidant activity of extract; increasing with the increment of concentrationof plant extract was revealed. ethanolic extract of artemisia haussknechtii inhibited both grampositiveand gram- negative bacteria. mic of the extract against yeast was the lowest (2.5 μg/ml).conclusion: a known anti-bacterial compound (camphor) was one of major components in theessential oil, ethanolic extract showed good anti-oxidant activity and also extract inhibited growthof both gram positive and gram negative bacteria and fungi. these findings supported sometraditional use of this plant.