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Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
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نویسنده
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carvalho f.r. ,vassão r.c. ,nicoletti m.a. ,maria d.a.
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منبع
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journal of venomous animals and toxins including tropical diseases - 2010 - دوره : 16 - شماره : 2 - صفحه:324 -341
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چکیده
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The aim of the present work was to study the effect of the crude extract of curcuma zedoaria on peripheral blood cells and tumor progression in c57bl/6j mice injected with b16f10 murine melanoma cells. the intraperitoneal therapy showed a significant increase in total white and red blood cell counts,a decrease in peritoneal cell number and tumor volume reduction,whereas the oral administration revealed a noteworthy augmentation only in total leukocyte count. these results contribute to evaluate the importance of alternative treatments that employ phytotherapic compounds against tumor progression and its possible immunomodulation.
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کلیدواژه
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Curcuma zedoaria; Hematology; Melanoma; Tumor
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آدرس
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laboratory of biochemistry and biophysics,butantan institute,são paulo,são paulo state, Brazil, laboratory of cell biology,butantan institute,são paulo,são paulo state, Brazil, department of pharmacy,university of são paulo,são paulo,são paulo state, Brazil, laboratory of biochemistry and biophysics,butantan institute,são paulo,são paulo state, Brazil
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Authors
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