Strategies in 'snake venomics' aiming at an integrative view of compositional,functional,and immunological characteristics of venoms

This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms,and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional,toxic,and immunological characteristics of venoms. some recent developments in this field are summarized,highlighting how strategies have evolved from the mere cataloguing of venom components (proteomics/venomics),to a broader exploration of their immunological (antivenomics) and functional (toxicovenomics) characteristics. altogether,the combination of these complementary strategies is helping to build a wider,more integrative view of the life-threatening protein cocktails produced by venomous snakes,responsible for thousands of deaths every year. © 2017 the author(s).