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ANTI PROLIFERATIVE ACTIVITIES OF 32 MALAYSIAN PLANT SPECIES IN BREAST CANCER CELL LINES
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نویسنده
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Nurhanan M. Y. ,Asiah O. ,Mohd Ilham M. A. ,Siti Syarifah M. M. ,Norhayati I. ,Lili Sahira H.
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منبع
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journal of tropical forest science - 2008 - دوره : 20 - شماره : 2 - صفحه:77 -81
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چکیده
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Anti-proliferative activities of 32 malaysian plant species in breast cancer cell lines. anti-proliferative activities of 143 crude extracts obtained from 32 plants collected from the rain forests of pahang, malaysia, were evaluated in two breast cancer cell lines, i.e. mcf-7 and t47d, obtained from the american type culture collection, usa. the objective of this study was to bioprospect a list of plants to find out their potential to be developed into anti-cancer drug(s), by means of bioassay guided isolation procedure. after performing sulforhodamine-b assay, 13 crude extracts from 11 plant species were found to have active anti-proliferative effects (ic50≤ 100μg ml-1)
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کلیدواژه
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MCF-7 and T47D cells ,active plant extracts ,forest reserves ,Pahang
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آدرس
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Forest Research Institute Malaysia, Malaysia, Forest Research Institute Malaysia, Malaysia, Forest Research Institute Malaysia, Malaysia, Forest Research Institute Malaysia, Malaysia, Forest Research Institute Malaysia, Malaysia, Forest Research Institute Malaysia, Malaysia
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Authors
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