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   prescribing trends of atrial fibrillation patients who switched from warfarin to a direct oral anticoagulant  
   
نویسنده hale zachary d. ,kong xiowen ,haymart brian ,gu xiaokui ,kline-rogers eva ,almany steve ,kozlowski jay ,krol gregory d. ,kaatz scott ,froehlich james b. ,barnes geoffrey d.
منبع journal of thrombosis and thrombolysis - 2017 - دوره : 43 - شماره : 2 - صفحه:283 -288
چکیده    Direct oral anticoagulant (doac) agents offer several lifestyle and therapeutic advantages for patients relative to warfarin in the treatment of atrial fibrillation (af). these alternative agents are increasingly used in the treatment of af, however the adoption practices, patient profiles, and reasons for switching to a doac from warfarin have not been well studied. through the michigan anticoagulation quality improvement initiative, abstracted data from 3873 af patients, enrolled between 2010 and 2015, were collected on demographics and comorbid conditions, stroke and bleeding risk scores, and reasons for anticoagulant switching. over the study period, patients who switched from warfarin to a doac had similar baseline characteristics, risk scores, and insurance status but differed in baseline crcl. the most common reasons for switching were patient related ease of use concerns (37.5%) as opposed to clinical reasons (16.5% of patients). only 13% of patients that switched to a doac switched back to warfarin by the end of the study period.
کلیدواژه atrial fibrillation ,dabigatran ,rivaroxaban ,apixaban ,doac ,noac
آدرس chi-baylor st. luke’s medical center, texas heart institute, usa, university of michigan cardiovascular center, usa, university of michigan cardiovascular center, usa, university of michigan cardiovascular center, usa, university of michigan cardiovascular center, usa, william beaumont hospital, usa, huron valley sinai hospital, usa, henry ford hospital, usa, henry ford hospital, usa, university of michigan cardiovascular center, usa, university of michigan cardiovascular center, usa
 
     
   
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