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   early function decline after ischemic stroke can be predicted by a nomogram based on age, use of thrombolysis, rdw and nihss score at admission  
   
نویسنده turcato gianni ,cervellin gianfranco ,cappellari manuel ,bonora antonio ,zannoni massimo ,bovi paolo ,ricci giorgio ,lippi giuseppe
منبع journal of thrombosis and thrombolysis - 2017 - دوره : 43 - شماره : 3 - صفحه:394 -400
چکیده    The availability of prediction tools for risk stratification after acute stroke is seen as a valuable perspective for tailored clinical management. this retrospective study was aimed to identify significant predictors of poor outcome in patients presenting with acute ischemic stroke, which could then be used for constructing a prediction model. the study population consisted of 837 patients admitted to the stoke unit of university hospital of verona (italy) for acute ischemic stroke within 12 h of symptoms onset. in multivariate analysis, age, use of thrombolysis, red blood cell distribution width (rdw) and nihss score at admission were found to be significant predictors of 3-month functional decline. a nomogram constructed by integrating these four variables exhibited an area under the curve of 0.832 for predicting functional impairment. the >80% risk cut-off derived from the nomogram was associated with 0.91 positive predictive value, whereas a risk probability <10% displayed 0.93 negative predictive value for predicting functional impairment. these results demonstrate that a prediction tool integrating some important clinical, laboratory and demographic variables enable an efficient risk stratification of poor outcome after acute stroke.
کلیدواژه stroke ,cerebral ischemia ,prediction ,outcome ,red blood cell distribution width ,nomogram
آدرس university hospital of verona, emergency department, italy, university hospital of parma, emergency department, italy, university hospital of verona, department of neurology and stroke unit, italy, university hospital of verona, emergency department, italy, university hospital of verona, emergency department, italy, university hospital of verona, department of neurology and stroke unit, italy, university hospital of verona, emergency department, italy, university of verona, section of clinical biochemistry, italy
 
     
   
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