patient compliance with an anticoagulation management system based on a smartphone application

We developed a novel anticoagulation management system (anticlot assistant) based on a smartphone application (app). this study was performed to evaluate patient compliance with anticlot assistant. this prospective case series study involved patients receiving warfarin therapy. the eligible patients were managed via anticlot assistant, and outcome data were analyzed. thirty patients were recruited. the mean time within the therapeutic range (ttr) was 56.5% ± 26.2% and the mean patient compliance with anticlot assistant was 52.7% ± 40.4%. the patients in good compliance group had higher ttr (65.6 ± 25.0% vs. 40.0 ± 21.0%, p = 0.009), lower time in the extremely low range (9.4 ± 10.6% vs. 27.4 ± 13.2%, p = 0.000) and in the extremely high range (1.3 ± 2.8% vs. 14.1 ± 22.3%, p = 0.004) than those in poor compliance group. logistic regression analysis revealed that receiving an education of > 6 years was the only independent predictor of good compliance (odds ratio 8.400, 95% confidence interval 1.274–55.394, p = 0.027). patient compliance is critical important for good outcomes and it might increase with improvements in education and more widespread use of information technology. although further improvement is needed, anticlot assistant is promising and this study offered valuable experiences for further research.