off-pump technique and replacement therapy for coronary artery bypass surgery in a patient with hemophilia b

Antithrombotic treatment and perioperative management in patients with hemophilia remains a challenge. as life expectancy in these patients is increasing, a concern about cardiovascular diseases is emerging. herein we present the case of a 68 year-old patient with mild hemophilia b and multivessel coronary disease who underwent coronary artery bypass grafting (cabg) surgery. off-pump surgery with continuous infusion fix treatment was performed successfully with stable factor ix levels, and no bleeding or thrombotic complications. there is a paucity of cases reported regarding management of cabg in this population. to our knowledge, this is the first patient with mild hemophilia b that underwent cabg surgery with off-pump technique, that seems to be a secure and effective procedure.