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persisting autoimmune heparin-induced thrombocytopenia after elective abdominal aortic aneurysm repair: a case report
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نویسنده
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roberge guillaume ,tritschler tobias ,macgillivray caleb ,dufresne laurence ,nagpal sudhir kumar ,scarvelis dimitrios
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منبع
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journal of thrombosis and thrombolysis - 2020 - دوره : 50 - شماره : 3 - صفحه:674 -677
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چکیده
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Persisting heparin-induced thrombocytopenia (hit) is characterized by ongoing thrombocytopenia more than 7 days after stopping heparin. it is part of cases referred to as autoimmune hit (ahit). in contrast to typical hit cases, ahit involves heparin-independent platelet activation mechanism highlighted by a strongly positive functional assay done without heparin. we report the first case of persisting hit after an elective abdominal aortic aneurysm repair presenting with arterial and venous thrombosis, and describe the potential role of intravenous immunoglobulin in such patients.
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کلیدواژه
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case report ,heparin ,thrombocytopenia ,thrombosis ,immunoglobulin
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آدرس
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university of ottawa, ottawa hospital research institute, department of medicine, canada. université laval, centre hospitalier universitaire de québec, hôpital st-françois d’assise, department of general internal medicine, canada, university of ottawa, ottawa hospital research institute, department of medicine, canada. bern university hospital, university of bern, department of general internal medicine, switzerland, university of ottawa, clinical epidemiology program, ottawa hospital research institute, thrombosis research group, canada, university of ottawa, the ottawa hospital, division of vascular surgery, canada, university of ottawa, the ottawa hospital, division of vascular surgery, canada, university of ottawa, ottawa hospital research institute, department of medicine, canada
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Authors
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