Pathologic findings of anthraco-silicosis in the lungs of one humped camels (Camelus dromedarius) and its role in the occurrence of pneumonia [Tek hörgüçlü develerde (Camelus dromedarius) anrako-silikozisin akciǧerlerdeki patolojik bulgulari{dotless} ve pömoni oluşumundaki rolü]

Pneumoconiosis is an occupational lung disease which occurs by the accumulation of inhaled organic and inorganic particles in the pulmonary parenchyma. these particles interfere with the defense mechanisms of the lungs. this study was designed to describe the gross and histopathological features of pneumoconiosis in the lungs and its relation with occurrence of pneumonia in camels. 150 pneumonic and 100 healthy lungs were examined for pneumoconiosis in pathologic level. macroscopic lesions of pneumoconiotic lungs were related to pneumonia and no remarkable features of pneumoconiosis were observed in the examined tissues. pneumoconiosis was diagnosed in 43 out of 150 lungs with pneumonic lesions. grossly healthy lungs did not show pneumoconiosis. out of 43 pneumoconiotic lungs,93% (n=40/43) were associated with interstitial pneumonia. also,pneumoconiosis occurred in 2.32% (n=1/43) and 4.65% (n=2/43) of lungs with suppurative bronchopneumonia and bronchointerstitial pneumonia,respectively. histopathologic findings related to pneumoconiosis were characterized by varying degrees of diffuse to nodular fibrosis as well as mild to heavy accumulations of mixed carbon and silicon dusts. interlobular and interalveolar septa of alveoli were thickened by fibrosis and infiltration of mononuclear inflammatory cells. crystalline silicon particles were in different shapes including filamentous,oblong and polygonal. anthraco-silicosis particles were observed inside and outside of macrophages more adjacent to the vessels and bronchioles as well as lymphocytes infiltration. the color of particle aggregations was different from scant gray to brown or dense black,depending on the amount of silicon or carbon dust deposition. in the lungs,areas with prominent deposition of crystalline silica rather than carbon were gray to light brown and focal interstitial fibrosis was occurred. the present study suggests a positive causal relationship between pneumoconiosis and pneumonia. it seems these particles predispose animals to pulmonary diseases especially various type of pneumonia.