Changes in the activity of aspartate- and alanine aminotransferase in dogs with experimentally induced Staphylococcus aureus infection [Köpeklerde deneysel oluşturulan Staphylococcus aureus enfeksiyonunda aspartat ve alanin aminotransferaz aktivitelerindeki deǧişimler]

The main purpose of this study was to evaluate the aspartate aminotransferase (ast) and alanine aminotransferase (alt) plasma concentrations in dogs with experimentally-induced staphylococcus aureus infection. correlations between ast,alt and respiratory rate (rr),pulse rate (pr) and internal body temperature (ibt) were also calculated. bacterial suspension with density of 3.1×109 cfu/ml was subcutaneously injected to 9 mongrel 2 years old male dogs whereas 6 other dogs served as negative controls. the concentrations were determined using commercial kits before application (0 h),6,24,48,72 h and 7,14,21 days after. the aminotransferase concentrations were higher in infected dogs than in the controls - ast peaked on days 7 and 14,and alt - at the 72nd h. strong positive correlations were recorded between alt and ast concentrations and between rr and ibt. it was observed that the transaminases activities were slightly affected by the experimentally induced staphylococcal infection in dogs.