Evaluation of serum haptoglobin,ceruloplasmin and pseudocholinesterase levels in cows with botulism [Botulismuslu ineklerde serum haptoglobulin,seruloplazmin ve pseudokolinesteraz seviyelerinin değerlendirilmesi]

The aim of this study was to determine serum pseudocholinesterase,rheumatoid factor,troponin i,c-reactive protein,caeruloplasmin,haptoglobin,urea,creatinin,creatinin kinase (ck),phosporus,calcium,alanine aminotransferase (alt) and aspartate aminotransferase (ast) in cows with or without botulism. the study included 15 holstein cows aged two to five years as the botulism group and control group consisting of 10 healthy cows. the group included both pregnant and dry period cattle. serum concentration of all the parameters were measured using an autoanalyzer and nefelometre equipment bnii. mice inoculation test was performed to make diagnosis and clostridium botulinum type c and d toxins were determined in silage and blood that cows with botulism. serum troponin i,c-reactive protein,rheumatoid factor,creatinine,creatinine kinase,phosphorus,calcium and ast did not differ significantly between two groups. biochemistry analysis of serum showed that in the botulism group haptoglobin,caeruloplasmin and urea were higher and that pseudocholinesterase and alanine aminotransferase were lower than in the control group. serum haptoglobin,caeruloplasmin,urea,alanine aminotransferase and especially pseudocholinesterase concentrations may prove beneficial to the prognosis of botulism. © 2016,veteriner fakultesi dergisi. all rights reserved.