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Immunohistochemical distribituon of COX-1,COX-2,and TGFβ-1 in the duodenum of rats treated with capsaicin [Capsaicin uygulanan sıçanların duodenumda COX-1,COX-2 ve TGFβ-1’in immünohistokimyasal dağılımı]
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نویسنده
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bakir b. ,eliş yildiz s. ,karadağ sari e. ,asker h. ,nazli m.
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منبع
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journal of the faculty of veterinary medicine, kafkas university - 2016 - دوره : 22 - شماره : 3 - صفحه:333 -338
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چکیده
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The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (cox-1),cyclooxygenase-2 (cox-2) and transforming growth factor β-1 (tgfβ-1) in rats. rats were divided into two groups (n =10 in each group). experimental group treated with capsaicin (1 mg/kg,subcutaneously) was injected in 10% ethanol,1% tween and 80% distilled water everyday for a period of one week and in not injected control group. localisations of cox-1,cox-2 and tgfβ-1 were observed in villus and crypt ephitelial cells,and smooth muscle cells. in conclusion,in this study,capsaicin administration was found to increase the release of cox-1 and cox-2,and tgfβ-1. © 2016,veteriner fakultesi dergisi. all rights reserved.
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کلیدواژه
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Capsaicin; Cyclooxygenase; Duodenum; Transforming growth factor β-1
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آدرس
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department of histology - embryology,namik kemal university,tekirdag, Turkey, school of health sciences,kafkas university,kars, Turkey, department of histology - embryology,kafkas university,kars, Turkey, department of histology - embryology,kafkas university,kars, Turkey, department of histology - embryology,mugla sıtkı kocman university,mugla, Turkey
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Authors
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