Evaluation of bone mineral density in premenopausal women with type-2 diabetes mellitus in Zahedan, southeast Iran

Objective: to determine the bmd in premenopausal women with type-2 diabetes mellitus.methods: this case-control study was performed on 60 premenopausal women with type-2 diabetes mellitus and 60 normal premenopausal subjects. the groups were not completely matched regarding bmi; but they were in the range of obesity. bone mineral density was determined using dual energy x-ray absorptiometry (dxa) to define bone mineral density (bmd) in second to fourth lumbar vertebrae and the neck of the femur (g/cm2).results: the results showed that bmd, t- and z-score of femoral neck, total femur, l2, and ward's were not significantly different between type 2 diabetic and normal premenopausal women (p>0.5). a significant increase of l3 bmd and l2-l4 z-score was observed in diabetic group (p<0.05). in addition bmd, t- and z-score of l4 were significantly higher in type 2 diabetic women than normal premenopausal women (p<0.05).conclusion: higher bmd was noted over the spine in diabetic group which may be due to higher bmi in this group.