Assessing two methods of repair of duodenal defects, jeujenal serosal patch and jejunal pedicled flap, (an experimental animal study)

Objective: to evaluate the outcomes of jejunal serosal patch and jejunal pedicled flap procedures for the repair of duodenal injuries. methods: the experimental animal-model study was conducted at shiraz university of medical sciences, iran, in february 2013. ten mixed-breed male dogs were selected and randomly divided into groups a and b. after general anaesthesia, a large duodenal defect was created in all animals. the defect was repaired with jejunal pedicled flap in group a and jejunal serosal patch in group b. microscopic healing was scored according to epithelialisation, collagenisation, inflammation, ulcer and necrosis of samples. kolmogorov-smirnov and independent t-test were used to indicate normal distributions of data and statistical differences between the two groups respectively. results: the weight of the animals ranged between 23 and 37kg and the age range was 12-16 months. all dogs survived the procedures. anastomotic leakage, intra-abdominal abscess or intestinal obstructions were not detected in gross examination. healing score was significantly higher in the group a than group b (p<0.011). however, in terms of surgical findings, no significant difference was detected between the groups (p>0.05). conclusion: applying jejunal pedicled flap for repairing large duodenal defects would lead to better histologic outcomes compared to jejunal serosal patch in dogs.