Subacute sclerosing panencephalitis presenting as rapidly progressive young-onset dementia

Onset of dementia before 65 years of age is termed as young-onset dementia (yod). very little literature exists regarding the clinical features and diagnoses of dementia in younger individuals. we present a case series of four patients of age 10 to 23 years with severe dementia within 18 months of clinical onset (rapidly progressive dementia). three patients had generalised periodic complexes typical of subacute sclerosing panencephalitis (sspe) on electroencephalogram (eeg). all patients had elevated cerebrospinal fluid (csf) igg measles antibodies. our case series highlights that sspe is an important cause of rapidly progressive yod in developing countries like india.