Vitamin E and its clinical challenges in cosmetic and reconstructive medicine with focus on scars; a review

Hypertrophic scars are abnormal scars that develop after wound-healing, especially in some ethnic backgrounds. the after-effects of these scars result in depression, post-traumatic stress syndrome, anxiety, impaired self-esteem and quality of life. treatment of these scars still is a subject of different studies and is a challenging issue in reconstructive medicine. we reviewed the current published articles about the effects of vitamin e on scar formation and its clinical effectiveness. the application of vitamin e is popular interest, but it still needs more clinical studies to establish its perceived outcomes