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Amiodarone therapy: don’t forget thyroid
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نویسنده
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Maseeh-uz-Zaman ,Fatima Nosheen ,Sajjad Zafar
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منبع
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journal of the pakistan medical association - 2012 - دوره : 62 - شماره : 3 - صفحه:268 -272
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چکیده
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Amiodarone is an effective anti-arrhythmic agent for control of various life threatening ventricular tachyarrhythmias but may give various side effects. clinically relevant thyroid dysfunction is not uncommon during amiodarone therapy and is caused by iodide excess and inhibition of deiodinase activity. amiodarone induced thyroid dysfunction varies from asymptomatic variation in thyroid function to clinically overt hypothyroidism and thyrotoxicosis. prolonged elimination and half life and associated complications warrant for rational prescribing and long term follow up.
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کلیدواژه
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Amiodarone ,Thyroid disorder ,Wolff-Chaikoff effect ,Hypothyroidism ,thyrotoxicosis
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آدرس
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Karachi Institute of Radiotherapy And Nuclear Medicine (KIRAN), Agha Khan University Hospital (AKUH), Department of Radiology, Pakistan, Karachi Institute of Radiotherapy And Nuclear Medicine (KIRAN), Agha Khan University Hospital (AKUH), Department of Radiology, Pakistan, Agha Khan University Hospital (AKUH), Agha Khan University Hospital (AKUH), Department of Radiology, Pakistan
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Authors
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Maseeh-uz-Zaman
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