Increase in serum alkaline phosphatase due to fatty meal in undergraduate students of Khyber Medical University,Khyber Pakhtunkhwa

Objective: to evaluate the effect of fatty meal on intestinal alkaline phosphatase. methods: the cross-sectional study was conducted at khyber medical university,peshawar,pakistan from march to april 2014 and comprised young healthy individuals 18-25 years of age. whole blood samples were collected from the subjects in ethylenediaminetetraacetic acid anti-coagulated and plane serum tubes. for blood group analysis,blood group anti sera were used,while for serum alkaline phosphatase,a chemistry analyser was used. alkaline phosphatase levels in the blood before and after breakfast were compared. results: of the 177 subjects,there were 139(78.5%) men and 38(21.4%) women. mean fasting alkaline phosphatise level was 144.22+/-75.57,while mean random value was 174.15+/-96.70 (p=0.001). conclusion: serum alkaline phosphatise must be analysed in fasting state early in the morning. © 2016,pakistan medical association. all rights reserved.