Asymmetrical dimethyl arginine in type 2 diabetic patients with coronary artery disease

Objective: to compare clinical and biochemical parameters for type 2 diabetic patients having coronary artery disease with controls. methods: the analytical,cross-sectional study was conducted at khyber medical college,peshawar,pakistan,for a period of one year between 2010 and 2011,and comprised two groups; group a had normal controls,while group b had type 2 diabetic patients with coronary artery disease. clinical parameters were blood pressure and body mass index. blood was centrifuged for blood sugar,glycosylated haemoglobin,total cholesterol,high-density lipoprotein,low-density lipoprotein,triglyceride and asymmetrical dimethylarginine. spss 15 was used to analyse data. results: of the 150 subjects,there were 75(50%) each in group a and group b,which had the mean age of 50.8±80 years and 53.4±52 years,respectively. both systolic and diastolic blood pressure and body mass index were raised and an elevated level of serum asymmetric dimethylarginine,fasting blood sugar,total cholesterol,triglycerides,glycosylated haemoglobin was noted among group b patients (p<0.05). conclusion: all clinical and biochemical parameters were found raised among diabetic patients with coronary artery disease. © 2016,pakistan medical association. all rights reserved.