Fractionated stereotactic radiosurgery for vestibular schwannomas using cyberknife: A single institution experience

Objective: to assess tumour control,hearing preservation status,and complication ratio after fractionated stereotactic radiosurgery/radiotherapy by using cyberknife device in patients with vestibular schwannomas. methods: this retrospective study was conducted at izmir ataturk research and tranining hospital,turkey,and comprised data of vestibular schwannomas patients treated with stereotactic radiosurgery/radiotherapy from march 2010 to december 2013. the patients were subjected to a dose ranging from 12 to 30gy using cyberknife system with an average of three fractions. spss 17 was used for data analysis. paired t-test and pearson's chi-square test were used to compare clinical parameters between groups. p<0.05 was considered significant. results: of the 41 patients,26(63.4%) were women and 15(36.6%) were men. the median follow-up duration after stereotactic radiosurgery/radiotherapy was 25 months (interquartile range: 9-44 months). radiographic control evaluation ratio was 95.7% with a median follow-up of 3 years (iqr: 18.5 months). results of 23(56%) patients showed stabile response,17(42%) regression response and 1(2%) progression response. there were no statistically significant changes between pre- and post-stereotactic radiosurgery/radiotherapy symptoms (p>0.05). one (2.4%) patient reported new onset facial paresis. conclusion: stereotactic radiosurgery/radiotherapy treatment of vestibular schwannomas resulted in a good ratio of tumour control. hearing preservation status and ratios of toxicity were comparable to published literature. © 2016,pakistan medical association. all rights reserved.