Investigation of the interactions and adsorption of ovalbumin with titanium dioxide and zirconia surfaces [Ovalbüminin titanyum dioksit ve zirkonya yüzeylerle etkileşimi ve adsorpsiyonunun araştirilmasi]

Knowing the interactions between the protein molecules and the biomaterial surfaces is important in a number of applications in biomedical technologies and materials engineering. the lack of knowledge on this topic due to the complexity of the protein molecular structures and their adsorption necessitates carrying out research work in order to solve the problems related with the protein-surface interactions. protein adsorption is influenced by many parameters such as the properties of proteins,ph,concentration,ionic strength and temperature. the aim of this study is to investigate the ovalbumin adsorption from aqueous solutions on tio2 and zro2,to study the effects of solution ph,temperature and adsorbent dosage on adsorption; to investigate the adsorption kinetics,protein-metal oxide interactions,and to determine the conditions controlling the adsorption. the interactions and adsorption of ovalbumin protein with tio2 and zro2 powders in solution environment were investigated in a batch adsorption system. adsorption experiments were carried out in ph 5,6.4,8 environment at 20,25,30 °c. the effect of adsorbent dosage was also investigated by the addition of different amounts of tio2/zro2 in the range 0.5-1.0 g/l. results have shown that the adsorbed amount of ovalbumin increases with increasing temperature and adsorbent dosage,but decreases with increasing ph. the increase of contact surface with increasing adsorbent dosage increases protein adsorption. the zeta potential measurement results supported that the interactions between ovalbumin with tio2 and zro2 were higher at ph 5,which is close to the isoelectric point of protein. the adsorption of ovalbumin onto tio2 and zro2 at different temperatures and solution ph conditions followed first order kinetics with a better fit for both adsorbents.