Role of prophylactic antibiotic in elective laparoscopic cholecystectomy.

This prospective study was conducted to investigate the efficacy of single-dose ceftazidime as a prophylactic antibiotic to prevent surgical site infections in low-risk patients undergoing lc. two hundred patients included in the study were randomly divided into two groups (100 each): g1: patients received intravenous ceftazidime within 60 minutes prior to surgery and g2: received intravenous placebo (10 ml isotonic sodium chloride 0.9% solution). all patients were invited for examination 10,20 and 30 days post-operatively and any post-operative complications were recorded and managed. preoperatively; there was no significant differences existed between the 2 groups regarding sex,age; body mass index and asa score. also,the duration of lc surgery,incidence of intra-operative gallbladder perforations and spill of bile or stones,incidents of intra-operative bleeding from either cystic artery or gall bladder liver bed and mean postoperative hospital stay were found not significantly different between the 2 groups. post operatively there was no statistical difference regarding the surgical site infection between the two groups.