Impact of fibrosis on response to interferon therapy in Egyptian HCV patients.

Hepatitis c virus (hcv) infection is a global health problem which can lead to liver cirrhosis or hepatocellular carcinoma in one-fifth of chronically infected patients. hcv-4 infection is common in the middle east and africa,with an extraordinary high prevalence in egypt. interferon is a cytokine,a specific protein that is no stranger to the human body. in fact,the human body is constantly making interferon,and makes even greater amounts when trying to fight off an intruder,such as a virus. this work studied the impact of liver fibrosis on the efficacy of interferon in treating hcv.