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Dopamine and tyramine derived amides from Suaeda fruticosa
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نویسنده
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khan j. ,saleem m. ,riaz n. ,nazir m. ,jabbar a. ,ashraf m. ,ismail t. ,ghaffar a. ,arshad m.
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منبع
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journal of the chemical society of pakistan - 2015 - دوره : 37 - شماره : 1 - صفحه:111 -114
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چکیده
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Summary: phytochemical investigations of suaeda fruticosa resulted in the isolation of two new dopamine-derived amides: n-(4-hydoxy-3-methoxyphenylethyl)-hexacosanamide (1) and n-(4- hydoxy-3-methoxyphenylethyl)-tetracosanamide (2),along with five known tyramine-derived amides: n-(4-hydroxyphenethyl)-hexacosanamide (3),n-(4-hydroxyphenethyl)-octacosanamide (4),tetracosunoyltyrumine (5),n-docosanoyltyrumine (6),and crotamide b (7). their structures were elucidated due to the combination of various spectroscopic data including 1d- and 2d-nmr techniques and high resolution mass spectrometry. all the isolates (1-7) were tested and found to be inactive against α-glucosidase,acetylcholinesterase,butyrylcholineste,lipoxygenase and dpph free radical. © 2015,chemical society of pakistan. all rights reserved.
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کلیدواژه
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Biological studies; Characterization; Secondary metabolites; Suaeda fruticosa
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آدرس
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department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur,bahawalpur,pakistan,institute of pharmaceutical biology,university of bonn,nussallee-6, Germany, department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of biochemistry and biotechnology,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of biochemistry and biotechnology,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, department of chemistry,baghdad-ul-jadeed campus,islamia university of bahawalpur, Pakistan, hej research institute of chemistry,international centre for chemical and biological sciences (iccbs),university of karachi, Pakistan
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Authors
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