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Synthesis leishmanicidal activities of bis-Schiff bases of isatins
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نویسنده
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khan m. ,khan k.m. ,rahim f. ,samreen h. e. j. research institute of chemistry ,perveen s. ,karim a. ,imtiazuddin department of chemistry ,choudhary m.i.
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منبع
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journal of the chemical society of pakistan - 2015 - دوره : 37 - شماره : 3 - صفحه:520 -526
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چکیده
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Twenty seven (27) derivatives of bis-schiff bases of isatins 1-27 were studied for their leishmanicidal potential. out of twenty seven (27) analogs,five exhibited varying degree of leishmanicidal activity with ic50 values 44.86 ± 0.66,65.27 ± 0.38,76.58 ± 0.30,46.51 ± 0.36,and 84.05 ± 0.23 μm,and rests of the compounds showed no leishmanicidal activity. © 2015,chemical society of pakistan. all rights reserved.
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کلیدواژه
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bis-Schiff bases; Isatins; Leishmanicidal activity
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آدرس
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h. e. j. research institute of chemistry,international center for chemical and biological sciences,university karachi,karachi,pakistan,department of chemistry,abdul wali khan university, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university karachi,karachi,pakistan,department of chemistry,hazara university, Pakistan, international center for chemical and biological sciences,university karachi, Pakistan, pcsir laboratories complex,karachi,shahrah-e-dr. salimuzzaman siddiqui, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university karachi, Pakistan, quaid-i-azam university, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university karachi, Pakistan
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Authors
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