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Synthesis,characterization,theoretical calculations and anti-tumor study of 2-aminopyridine trifluorotitanium (IV) complex
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نویسنده
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shabani f. ,bozorghi s.j. ,sheykhpoor m.
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منبع
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journal of the chemical society of pakistan - 2015 - دوره : 37 - شماره : 6 - صفحه:1135 -1142
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چکیده
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A new titanium compound that is 2-aminopyridine trifluorotitanium (iv) complex was synthesized and identified. this complex was prepared through the reaction of 2-amino pyridine and titanium tetrafluoride salt of in acetonitrile. identification and characterization of complex was performed by elemental analysis and spectroscopic methods. structural and spectroscopic study of the mentioned complex was carried out at dft-b3lyp/6-311g level of theory. this new compound was used to biological studies; and its anticancer properties against the two types of cancer cells such as k562 (human chronic myeloid leukemia) and jurkat (human t lymphocyte carcinoma) was revealed.
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کلیدواژه
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2-Aminopyridine trifluorotitanium (IV) ,theoretical study ,anti-tumor ,K562 ,Jurkat; Ti (IV) complex
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آدرس
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chemistry department,science faculty,arak branch,islamic azad university, ایران, chemistry department,science faculty,hamedan branch,islamic azad university, ایران, department of cellular and molecular biology,research center of new technologies in life science engineering, ایران
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Authors
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