|
|
|
|
Naturally occurring antifungal aromatic esters and amides
|
|
|
|
|
|
|
|
نویسنده
|
ali m.s. ,shahnaz h.e.j. research institute of chemistry ,tabassum s. ,ogunwande i.a. ,pervez m.k. ,ibrahim o.a.
|
|
منبع
|
journal of the chemical society of pakistan - 2010 - دوره : 32 - شماره : 4 - صفحه:565 -570
|
|
چکیده
|
During the search of antifungal natural products from terrestrial plants,a new long chained aromatic ester named grandiflorate (1) along with spatazoate (2) from portulaca grandiflora and n-[2- methoxy-2-(4-methoxyphenyl) ethyl-trans-cinnamide (3) and aegeline (4) from solanum erianihum of nigeria were isolated and tested against six fungal species. the known constituents 2-4 have not bee reported so far from mentioned investigated plants. structures of the isolated compounds were elucidate with the aid of spectroscopic techniques including two dimensional nmr experiments. among th compounds 1-4,the esters (1-2) found more potent than amides (3-4) against candida albicans an aspergillus flavus. the new compound grandiflorate (1) gave response against all tested fungal specie while aegeline (4) was found to give lowest inhibition during this study.
|
|
|
|
|
آدرس
|
h.e.j. research institute of chemistry,international center for chemical and biological sciences (iccbs),university of karachi, Pakistan, international center for chemical and biological sciences (iccbs),university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences (iccbs),university of karachi, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences (iccbs),university of karachi,karachi-75270,pakistan,department of chemistry,lagos state university,ojo, Nigeria, h.e.j. research institute of chemistry,international center for chemical and biological sciences (iccbs),university of karachi,karachi-75270,pakistan,leather research center,pakistan council for scientific and industrial research, Pakistan, h.e.j. research institute of chemistry,international center for chemical and biological sciences (iccbs),university of karachi,karachi-75270,pakistan,department of chemistry,ibadan university, Nigeria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|