Synthesis,spectral investigation (1H,13C) of new (N,O and S based) schiff bases and evaluation of their antimicrobial activities

Three new series of biologically active amino substituted schiff bases (1-12) with general formula,r1n=chr2 (r1 = 2-amino-benzthiazole,4-amino-salicylic acid and 4-aminophenol; r2 = benzaldehyde,2-chloro-benzaldehyde,4-chloro-benzaldehyde,salicylaldehyde and vanillin) were synthesized by the reaction of three different amino substituted compounds and substituted aldehydes in ethanol. the synthesized compounds were characterized by different physico-chemical techniques like,melting point,elemental analysis,multinuclear nmr (1h,13c). the compounds were subjected for bioassay screening and showed promising antibacterial and antifungal activities using amoxicillin and ciprofloxacin as standard drugs.