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Allo-Imperatorin: A potent urease inhibitor from fresh unripe fruits of Aegle marmelos (rutaceae)
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نویسنده
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ali m.s. ,ahmed g. ,pervez m.k. ,lateef m. ,afza n. ,iqbal l.
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منبع
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journal of the chemical society of pakistan - 2011 - دوره : 33 - شماره : 6 - صفحه:960 -964
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چکیده
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During the search for bioactive constituents from different parts of aegle marmelos (rutaceae),the ethanol soluble portion of fresh unripe fruits yielded two known amides named aegeline (1) and 2-o-methyl aegeline (2),and five known coumarins named xanthotoxol (3),alloimperatorin (4),marmesin (5),marmin (6),7'-o-methylmarmin (7). structures of 1-7 were elucidated with the aid of spectroscopic techniques. all the isolated constituents (1-7) were tested for urease inhibition. allo-imperatorin was found the most potent among the all tested samples with the ic50 value 27.5 μm.
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آدرس
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h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi,karachi-75270,pakistan,leather research center,pakistan council for scientific and industrial research,karachi, Pakistan, pharmaceutical research center,pakistan council for scientific and industrial research laboratories complex,karachi, Pakistan, pharmaceutical research center,pakistan council for scientific and industrial research laboratories complex,karachi, Pakistan, pharmaceutical research center,pakistan council for scientific and industrial research laboratories complex,karachi, Pakistan
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Authors
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