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An efficient eco-friendly synthesis of Indole-Mannich base
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نویسنده
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khan k.m. ,rahim f. ,ambreen n. ,taha m. ,iqbal s. ,haider s.m. ,perveen s.
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منبع
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journal of the chemical society of pakistan - 2012 - دوره : 34 - شماره : 3 - صفحه:748 -757
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چکیده
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An efficient and simplified protocol for three component mannich reaction of indoles in water without using any catalyst is described. different functionalized indole mannich base synthesized in relatively short time with moderate to good yields. the advantages of this methodology are higher selectivity,simplicity,and shorter reaction time. to the best of our knowledge this is the first green protocol for indole mannich base reaction.
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کلیدواژه
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Environmentally friendly efficient synthesis; Higher selectivity; Mannich reaction; Shorter reaction time
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آدرس
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h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, h. e. j. research institute of chemistry,international center for chemical and biological sciences,university of karachi, Pakistan, pcsir labs complex,karachi,shahrah-e-dr. salimuzzaman siddiqui, Pakistan
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Authors
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